Development

Prediabetes

Prediabetes refers to individuals whose blood glucose levels are high but are not in the diabetes range (towards upper end of normal). Prediabetes is not a disease and should not be viewed as a clinical entity in its own right but rather as an increased risk for diabetes and cardiovascular disease (CVD). Prediabetes is associated with obesity (especially abdominal or visceral obesity), dyslipidemia with high triglycerides and/or low HDL cholesterol.

Normally, human bodies make the hormone insulin to control blood sugar. But in the case of prediabetes, this system doesn't work as well as it should, and they might not be able to make enough insulin after eating, or their bodies might not respond properly to the insulin.

20% of people in Europe, US and Japan have prediabetes

Growing Problem

Prediabetes is a growing problem affecting about 20% of the population in Europe, USA and Japan. There is a clear need for a new approach before complications develop into full-blown diabetes, cardiovascular disease and other metabolic diseases.

The Need for Novel Safe and Beneficial Products

According to 2016 statistics from the Centers of Disease Control and Prevention (CDC), 86 million Americans aged 20 and older are living with prediabetes. Prediabetics, in particular, have a large unmet need for safe and beneficial product.

Americans with prediabetes according to CDC

The Risks associated with Prediabetes

Prediabetes is a risk factor for diabetes and cardiovascular disease (CVD). Prediabetes is associated with obesity (especially abdominal or visceral obesity) and dyslipidemia with high triglycerides and/or low HDL cholesterol (American Diabetes 2018).